The United States has developed new compounds for the treatment of diabetes without related side effects

According to the Xinhua News Agency in London, a research report published on the British "Nature" website on September 4 said that American researchers have developed a new compound that can be used to treat diabetes. Compared with existing drugs, it can improve blood sugar. Level, but no related side effects.

Researchers from the Scripps Research Institute and other institutions in the United States reported that this new compound is named SR1664, and its principle of action is to help treat diabetes by interfering with the function of certain proteins.

The researchers used SR1664 and the existing hypoglycemic drug Avandia to treat experimental mice with diabetes. The results showed that both can improve the blood glucose levels of the experimental rats, but Avandia has side effects such as weight gain in the experimental rats. The new The compound has no related side effects. The compound also has no side effects such as Avandia and other hypoglycemic drugs that affect bone.

Patrick Griffin, who led the study, said that the target of SR1664 is the known diabetes treatment target, but its mechanism of action is unique, so it has both therapeutic functions and some side effects. Researchers will strive to develop drugs for clinical treatment on their basis. (Reporter Huang Kun)


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